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Stojanović et al. 2013
Autor Stojanović, G.  + , Đorđević, A.  + , Šmelcerović, A.  +
Autorenschaft Stojanović, G.; Đorđević, A.; Šmelcerović, A.;  +
Band 20  +
Formatierte Literaturausgabe (Kapitälchen) <div class="hanging-indent cite" style=
<div class="hanging-indent cite" style="" id="Stojanovi.C4.87_et_al._2013"><span style="font-variant:small-caps">Stojanović,<span></span> G., <span></span>Đorđević,<span></span> A. & Šmelcerović,<span></span> A.</span> <span style="white-space:nowrap;">1. Juni 2013</span>: <em>Do Other ''Hypericum'' Species Have Medical Potential as St. John’s Wort (''Hypericum perforatum'')?</em> In: ''Current Medicinal Chemistry.'' Bd. 20, Nr. 18, Bentham Science Publishers, S. 2273-2295 ([https://www.ingentaconnect.com/content/ben/cmc/2013/00000020/00000018/art00001 https:/​/​www.​ingentaconnect.​com/​content/​ben/​cmc/​2013/​00000020/​00000018/​art00001]).</div><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=journal&rfr_id=info%3Asid%2Foffene-naturfuehrer.de%3AStojanovi%C4%87+et+al.+2013&rft.atitle=Do+Other+%27%27Hypericum%27%27+Species+Have+Medical+Potential+as+St.+John%E2%80%99s+Wort+%28%27%27Hypericum+perforatum%27%27%29&rft.series=Current+Medicinal+Chemistry&rft.au=Stojanovi%C4%87%2C+G.%3B+%C4%90or%C4%91evi%C4%87%2C+A.%3B+%C5%A0melcerovi%C4%87%2C+A.%3B&rft.date=2013&rft.volume=20&rft.issue=18&rft.pages=2273-2295&rft_id=https%3A%2F%2Fwww.ingentaconnect.com%2Fcontent%2Fben%2Fcmc%2F2013%2F00000020%2F00000018%2Fart00001"> </span>
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Formatierte Literaturausgabe (Standard) <div class="hanging-indent cite" style=
<div class="hanging-indent cite" style="" id="Stojanovi.C4.87_et_al._2013">Stojanović,<span></span> G., <span></span>Đorđević,<span></span> A. & Šmelcerović,<span></span> A. <span style="white-space:nowrap;">1. Juni 2013</span>: <em>Do Other ''Hypericum'' Species Have Medical Potential as St. John’s Wort (''Hypericum perforatum'')?</em> In: ''Current Medicinal Chemistry.'' Bd. 20, Nr. 18, Bentham Science Publishers, S. 2273-2295 ([https://www.ingentaconnect.com/content/ben/cmc/2013/00000020/00000018/art00001 https:/​/​www.​ingentaconnect.​com/​content/​ben/​cmc/​2013/​00000020/​00000018/​art00001]).</div><span style="display: none;" class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=journal&rfr_id=info%3Asid%2Foffene-naturfuehrer.de%3AStojanovi%C4%87+et+al.+2013&rft.atitle=Do+Other+%27%27Hypericum%27%27+Species+Have+Medical+Potential+as+St.+John%E2%80%99s+Wort+%28%27%27Hypericum+perforatum%27%27%29&rft.series=Current+Medicinal+Chemistry&rft.au=Stojanovi%C4%87%2C+G.%3B+%C4%90or%C4%91evi%C4%87%2C+A.%3B+%C5%A0melcerovi%C4%87%2C+A.%3B&rft.date=2013&rft.volume=20&rft.issue=18&rft.pages=2273-2295&rft_id=https%3A%2F%2Fwww.ingentaconnect.com%2Fcontent%2Fben%2Fcmc%2F2013%2F00000020%2F00000018%2Fart00001"> </span>
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Jahr 2013  +
Literaturangabe Nummer 18  +
Monatsname Juni  +
Online https://www.ingentaconnect.com/content/ben/cmc/2013/00000020/00000018/art00001  +
Sammelwerk Current Medicinal Chemistry  +
Seiten 2273-2295  +
Seitenname Stojanović et al. 2013 +
Sortierschlüssel Stojanović,GĐorđević,AŠmelcerović,A2013DoOtherHypericumSpeciesHaveMedicalPotentialasStJohn’sWort(Hypericumperforatum)CurrentMedicinalChemistry  +
Stichwort ''Hypericum''  + , ''Hypericum annulatum''  + , ''Hypericum ascyron''  + , ''Hypericum barbatum''  + , ''Hypericum boissieri''  + , ''Hypericum elegans''  + , ''Hypericum foliosum''  + , ''Hypericum geminiflorum''  + , ''Hypericum hirsutum''  + , ''Hypericum humifusum''  + , ''Hypericum hyssopifolium''  + , ''Hypericum inodorum''  + , ''Hypericum montbretii''  + , ''Hypericum moseranum''  + , ''Hypericum patulum''  + , ''Hypericum perforatum''  + , ''Hypericum richeri''  + , ''Hypericum rochelii''  + , ''Hypericum rumeliacum''  + , ''Hypericum sampsonii''  + , ''Hypericum scabrum''  + , ''Hypericum thasium''  + , ''Hypericum triquetrifolium''  + , biological activities  + , chemical composition  + , non-volatile secondary metabolites  +
Tag 1  +
Titel Do Other ''Hypericum'' Species Have Medical Potential as St. John’s Wort (''Hypericum perforatum'')  +
Verlag Bentham Science Publishers  +
Zusammenfassung Among 484 Hypericum L. (Guttiferae/Hyperic
Among 484 Hypericum L. (Guttiferae/Hypericaceae) species, widespread in warm temperate areas throughout the world, only H. perforatum is widely used in official medicine. Hypericum perforatum has been reported as an antidepressant, antiviral, antimicrobial, anti-inflammatory, and a healing agent. The main constituents of the Hypericum species are naphthodianthrones, primarily represented by hypericin and pseudohypericin, phloroglucinol derivatives, especially hyperforin, and flavonoids, such as quercetin, quercitrin, hyperoside and rutin. Hypericin and pseudohypericin have been found to possess antiretroviral activity. Hyperforin may also have an important contribution to the antidepressant activity of Hypericum extracts. The content of the above active constituents in some Hypericum species is higher than in H. perforatum. Also, a number of studies of the biological activities of Hypericum species have shown that the most recognized species of this genus, H. perforatum, was not the most active. Comprehensive analysis of the published research on the chemical composition and biological activity, showed that H. richeri has a similar pharmacological potential as St. Jon`s wort. The species, with high content of naphtodianthrones,which might be used against viruses and retroviruses, are: H. androseamum,H. annulatum, H. barbatum, H. boissieri, H. elegans, H. hirsutum, H. hyssopifolium, H. humifusum, H. montanum. H. montbretii, H. triquetrifolium, H. richeri, H. rochelii, H. rumeliacum, H. thasium, andH. patulum. Very few species (e.g. H. inodorum and H. moseranum) contained the similar amounts of hyperforine as H. perforatum. Since hyperforin was recognized as one of the most crucial components for the antidepressive activity, it seems that H. perforatum barely has an alternative for this purpose. Plant species containing considerable amounts of other acylphloroglucinol derivatives have the potential to demonstrate antibacterial and cytotoxic activity. Some of these species are: H. sampsonii, H. ascyron, H. foliosum, H. geminiflorum and H. scabrum. However, only a few studies concerning the activity of extracts and isolated compounds were done in vivo. Also, data on the safe usage of Hypericum constituents as phytotherapeutics are scarce. Since some of Hypericum species are scarcely distributed or endemic as well as some of the secondary metabolites are presented in very small amounts, bio-production, especially endophytes, could represent an abundant and reliable source of pharmacologically active metabolites of Hypericum species for exploitation in pharmaceutical industry.
r exploitation in pharmaceutical industry.  +
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Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 +
Categories Literatur , Literatureintrag
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Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 + , Stojanović et al. 2013 +
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